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Efficacy

Evaluation Model

Evaluation Indicator

Repairing

Barrier-related genes in HaCaT cells

Expression of barrier-related genes (AQP3, FLG, Caspase-14 , Claudin-1, occludin)

Cell wound scratch assay

Skin mobility rate

SDS stimulated cell damage model in HaCaT cells

Cell vitality

3D skin damage model

Measurement of inflammatory factors (IL-6, IL-8, TNF-α, IL-1α, etc.)

3D skin damage model

Expression of barrier-related genes (AQP3, FLG, Caspase-14 , Claudin-1, occludin)